iScience | VOL. 25

Hybprinting for musculoskeletal tissue engineering.

Publication Date May 20, 2022


This review presents bioprinting methods, biomaterials, and printing strategies that may be used for composite tissue constructs for musculoskeletal applications. The printing methods discussed include those that are suitable for acellular and cellular components, and the biomaterials include soft and rigid components that are suitable for soft and/or hard tissues. We also present strategies that focus on the integration of cell-laden soft and acellular rigid components under a single printing platform. Given the structural and functional complexity of native musculoskeletal tissue, we envision that hybrid bioprinting, referred to as hybprinting, could provide unprecedented potential by combining different materials and bioprinting techniques to engineer and assemble modular tissues.

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Hybrid Bioprinting
Acellular Components
Printing Strategies
Rigid Components
Musculoskeletal Tissue
Soft Components
Hard Tissues
Cellular Components
Composite Constructs
Single Platform

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