Abstract

COVID-19 can lead to severe pneumonia, requiring mechanical ventilation. While increased sputum secretion could cause airway obstruction during mechanical ventilation, there are few reported cases in the literature. We report a case of a 65-year-old man with diabetes and severe COVID-19 pneumonia requiring mechanical ventilation and treated with hydroxychloroquine, azithromycin, nafamostat, and prone positioning. Initially, mechanical ventilation consisted of a heat moisture exchanger, endotracheal tube aspiration, and subglottic secretion drainage using a closed suction system. However, endotracheal tube impaction by highly viscous sputum occurred during this mechanical ventilation system. Replacing the endotracheal tube, the use of a humidifier instead of a heat moisture exchanger, and prone positioning contributed to the patient being weaned off mechanical ventilation. Although anti-aerosol measures are important for severe COVID-19 pneumonia, attention should be given to potential endotracheal tube impaction during mechanical ventilation.

Highlights

  • The SARS-CoV-2 infection, which first occurred in China in December 2019, has spread worldwide

  • The Japan Society of Intensive Care Medicine and Japanese Society of Respiratory Care Medicine have mentioned that airway impaction from increased sputum secretion is characteristic in patients with severe COVID-19 on mechanical ventilation, which is an issue to which healthcare workers should pay attention [4]

  • The Japan Society of Intensive Care Medicine and Japanese Society of Respiratory Care Medicine have mentioned that airway impaction from increased sputum secretion is characteristic in patients with severe COVID-19 on mechanical ventilation, which is an issue that healthcare workers should be aware of [4]

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Summary

Introduction

The SARS-CoV-2 infection (hereinafter, COVID-19), which first occurred in China in December 2019, has spread worldwide. We describe a patient with severe COVID-19 pneumonia for whom mechanical ventilation was complicated due to endotracheal tube impaction from sputum. Aspiration was not possible even when the suction pressure was increased, and the SpO2 and tidal volume remained below 90% and 100 mL, respectively, even at a positive end-expiratory pressure (PEEP) of 20 mmH2O and driving pressure of 30 mmH2O For this reason, we pushed the adhered matter into the trachea and removed the bronchoscope while aspirating again, and we managed to aspirate the Azuki bean-sized, 2020 Sugimoto et al Cureus 12(6): e8626. The lumen of the removed endotracheal tube was covered with highly viscous reddish-brown sputum (Figure 4) Both oxygenation and tidal volume improved after tube replacement, and from this point on, the use of the heat moisture exchanger was discontinued and replaced by a humidifier. The patient was transferred to another hospital for the rehabilitation of his swallowing and limb functions on Day 45

Discussion
Conclusions
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Disclosures
The Novel Coronavirus Pneumonia Emergency Response Epidemiology Team

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