Abstract
The aims of the current study were to detect different HPV types in Cuban patients with different grades of cervical intraepithelial neoplasia (CIN) and to assess the association between HPV infection and other risk factors involved in the development of cervical cancer in Cuban women. We analyzed 60 samples from women with a previous diagnosis of abnormal cytology (15 CIN-1 36 CIN-2 and 9 CIN-3) who were referred to the Gynecology and Obstetrics Department at Eusebio Hernandez Maternity Hospital in Havana Cuba by their primary clinics. Epidemiologic data were obtained from standardized questionnaires. The questionnaire was designed to provide information on sexual and reproductive behavior (reproductive and gynecological history sexual history and the age of the first intercourse) socioeconomic conditions cigarette smoking and oral contraceptive use. During the first visit to the hospital an informed consent was obtained from each patient. For HPV detection ectocervical and endocervical scrapings were used; Pap smears were also analyzed. Every patient underwent colposcopic examination which included two schematic drawings of the reactions of the acetic acid and Lugol solution. This method allowed the detection of leucoplastic lesions atypical transformation zones cervicitis colpitis and condylomatous lesions. (excerpt)
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