Abstract

In-laws spur intestinal imbalance A customary Dutch holiday gift box typically contains cookies and chocolate, but in 2016, the staff of the internal medicine and vascular medicine departments at Amsterdam University Medical Center got a little something extra from their colleagues in Max Nieuwdorp’s lab—two fecal-sample collection containers. The group had been brainstorming a fun microbiome-related study they could do around the holidays, and it’s fair to think that the holiday season, filled with travel, complicated family dynamics, and copious amounts of rich food, could throw your gut out of whack. On Dec. 23, before Christmas, and again on Dec. 27, MD-PhD student Nicolien de Clercq and then-undergraduate Myrthe Frissen collected the samples. “Everyone was in line to hand over their feces in our department,” de Clercq tells Newscripts, “which was pretty hilarious.” Three years later, their microbiome work has bloomed into a new paper: “The Effect of Having Christmas

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