Abstract
Two stimulating microelectrodes were inserted 0.5 mm apart in the rat's nucleus raphe magnus (NRM), giving a joint electrical threshold for suppression of the heat-evoked tail-flick reflex. Synchronous stimulation often required more current than predicted by consideration of each site's solitary threshold. Asynchronous stimulation required yet more current. We postulate that some NRM cells, perhaps corresponding to the ‘on-cells’ found previously by microelectrode recording, facilitate flexion and become relatively more influential at higher stimulus currents. We also postulate that the dominating cells that suppress flexion, possibly ‘off-cells’, operate optimally when firing simultaneously.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
