Abstract
The role of nitric oxide in cerebellar synaptic plasticity is controversial. Two recent papers on nitric oxide-(NO) and synaptic plasticity are discussed which use new methods for investigating the actions of NO and suggest that under certain conditions it is an essential anterograde messenger. In the light of current thinking about the diversity of expression of hippocampal LTP, should a presynaptic contribution to cerebellar LTD be re-examined? If NO acts orthogradely, might its product cGMP have a retrograde action? [CRÉPEL et al.; LINDEN; VINCENT]
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