Homoleptic vanadium(III) diacetone glucosides: how to make a Lewis acid chiral. Crystal structure of tris-(1,2:5,6-di-O-isopropylidene-α-D-glucofuranosato-κO3)-bis(pyridine)vanadium(III)

Abstract

The synthesis of the first homoleptic glucose derivative of a transition metal was achieved via the protonolysis of [V(C6H2Me3-2,4,6)3(thf)](thf = tetrahydrofuran) using the monoprotic ligand 1,2:5,6-di-O-isopropylidene-α-D-glucofuranose (HL). The complex [VL3] was converted by addition of pyridine (py) into [VL3(py)2] containing a metal chiral centre as shown by X-ray analysis.