Abstract
Abstract Objective The objective of this study was to assess whether the mitral homograft represents a valuable alternative for complete or partial mitral valve replacement. Methods Since 1993, 104 patients underwent mitral homograft replacement surgery. The mean age was 38 ± 15 years. The causes of mitral valve disease were rheumatic disease (n = 76), infective endocarditis (n = 24), and others (n = 4). Sixty-five of these procedures were total homografts, and 39 were partial homografts. Results The mean follow-up was 52 ± 35 months (maximum, 117 months). Overall hospital mortality was 4 (3.8%) of 104 patients and 2.5% versus 8.7% for patients without endocarditis and with endocarditis, respectively ( P P P = .09) Conclusion The risk of early dysfunction related to a mismatch between the mitral homograft and the patient's valve is the main pitfall of the technique. Beyond that stage, the results were comparable with those of bioprostheses in a cohort of young patients.
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