Abstract
Collagenous, anisotropic tissue such as tendon has proven resistant to fractionation by histotripsy, prompting the need to better understand and quantify bubble dynamics in anisotropic tissue. The elastic moduli in each axial direction were measured for collagen, fibrin, and polyacrylamide hydrogels prior to applying histotripsy; high-speed photography and cavitation emission data were used to evaluate bubble size and collapse strength. [Work supported by NIH R21EB027886.]
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