Abstract

Abstract A reproducible method to determine reduction in odontoblast number and variation in dentine thickness was devised. Using this method the pulp reaction patterns to Nobetec® (a modified zinc oxide‐eugenol cement) and Super Syntrex® (a silicate cement) in verve I monkeys were quantitated. This investigation showed that statistically significant reductions in odontoblast numbers were seen under cut dentinal tubules compared lo areas under a cavity with no cut tubules. Reparative dentine thickness was similar under both materials and the mean thickness doubled between 28 and 56 clays after cavity preparation. Both materials were (bund lo be irritant. It is suggested that quantitation of odontoblasts and reparative dentine thickness under cut dentinal tubules may be used as (he main criteria in pulpal studies in order to discriminate between test materials.

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