Abstract

Cashdollar and colleagues (1) describe a powerful combination of behavioral and magnetoencephalography data from healthy participants and patients with bilateral hippocampal sclerosis to support a role for the hippocampus in the active maintenance of configural-relational (C-R) information. This study reveals the importance of hippocampal-dependent theta synchronization of temporal and occipital regions in humans to C-R working memory, and how such coordination may contribute to the integration of visual information represented throughout the rostral-caudal extent of the ventral visual processing stream. These findings, therefore, add to a growing body of literature arguing for an involvement of the hippocampus in both long- and short-term relational memory.

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