Abstract

Cognitive deficits such as inattention and memory impairment are persistent symptoms in schizophrenia that respond poorly to treatment, contribute to poor prognosis, and have been associated with impaired activation of the dorsolateral prefrontal cortex (DLPFC). These researchers used a novel technique involving positron emission tomography to study prefrontal cortical and hippocampal function during episodic memory retrieval in 13 schizophrenics and 8 controls. Both schizophrenic patients …

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