Hipokalemik Paralizi ile Prezente Olan Primer Aldosteronizm: İki Olgu Sunumu

Abstract

Primary aldosteronism may appear with various clinical presentations. Primary aldosteronism presented with hypokalemic paralysis is a very rare condition. Case 1; a 33-year-old male was admitted to the emergency department with the complaint of muscle weakness affecting all four extremities (quadriparesis). The patient had a history of hypertension and despite triple antihypertensive therapy his blood pressure was around 160/100 mmHg in follow-up evaluations. In physical examination, upper and lower ekstremity motor strength was 1/5 and deep tendon reflexes were absent. Case 2; a 39-year-old female were admitted to the hospital with the complaint of muscle weakness and pain, difficulty in stair climbing. She had no history of hypertension. In her physical examination; blood pressure was 150/80 mmHg. There was weakness in muscle strength especially in the lower extremities, and decrease in deep tendon reflexes. Hypokalemia (1.4 and 1.7 mEq/L, respectively) and hyporeninemic hyperaldosteronism were determined in both of the patients' laboratory examination. Adrenal adenoma was detected in the magnetic resonance images of both cases and improvements in hypokalemia and hypertension were observed following laparoscopic adrenalectomy for aldosterone producing adenoma. We believe that primary aldosteronism should be kept in mind in differential diagnoses of patients having muscle weakness, hypertension, and hypokalemia.