Abstract
AbstractThe purpose of this report is to indicate the presence of high‐frequency pressure fluctuations that are superimposed upon intra‐arterial pressure curves in man, and to establish their significance as an indication of the presence of turbulent blood flow. Intracardiac pressure was obtained in 23 patients, utilizing catheter‐tip micromanometers. Velocity fluctuations indicative of turbulence were measured in 10 of these patients above the aortic valve. High frequency pressure fluctuations occurred in patients with elevated cardiac output, aortic valvular disease, subaortic stenosis, and atrial septal defect. Patients in whom high frequency velocity fluctuations were measured by hot film anemometry almost always showed high frequency pressure fluctuations on the pressure tracings. This indicated a qualitative relationship between the occurrence of turbulent or disturbed blood flow and the presence of high‐frequency pressure fluctuations. A qualitative relationship between fluctuating pressures and fluctuating velocities was also derived on the basis of fluid dynamic theory. Recognition that high‐frequency pressure fluctuations result from turbulent blood flow may be of value in the localization of turbulent blood flow which, in some instances, may relate to pathological processes.
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