Abstract
Understanding the underlying mechanisms leading to progressive muscle pathologies in spastic Cerebral Palsy remains a challenging field of research. Furthermore, Botulinum Neurotoxin-A (BoNT-A) is a frequent intervention to treat spasticity in CP but its effects on neuromuscular properties are not yet fully explored. High-density Electromyographic (HD-EMG) data have been collected before and after BoNT-A injections from children aged 5–15 years during isometric contractions of the ankle joint together with torque output, clinical assessments and demographic details. Data collected from a total of 13 children with and 29 children without spastic CP allow for between-group comparisons and are made available using Mendeley Data (https://doi.org/10.17632/3sbptrk54c.2 and https://doi.org/10.17632/3b98g5fyff.1).
Highlights
High-density electromyographic data during isometric contractions of the ankle joint in children with cerebral palsy pre and post Botulinum Neurotoxin-A (BoNT-A) treatment
Exclusion criteria for the CP group included severe cognitive or visual impairments interfering with the ability to cooperate with the experimental protocol, concomitant neurological diseases, BoNT-A injection within the previous 4 months, neurosurgical and lower-limb orthopaedics procedures within the previous 12-months, previous selective dorsal rhizotomy and/or intrathecal baclofen treatment
Individuals recruited for the TD group were gender- and age-matched within ±12-months to children in the CP group
Summary
Inclusion criteria for the CP group included spasticity affecting the lower limb requiring BoNT-A treatment. Children in the TD group were required to be healthy without neurosurgical or lower-limb orthopaedics procedures within the 12-months prior to participation. All participants and their parents or legal guardian provided written informed assent/consent and the measurements were conducted following the guidelines outlined by the Southern Health and Disability Ethics Committee, New Zealand (HDEC; Ethics reference: 17/STH/215). Individuals recruited for the TD group were gender- and age-matched within ±12-months to children in the CP group. Demographic details (age, gender, height, weight, BMI and body side assessed) of all participants can be obtained from the data available with Mendeley Data [3,4]
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