Abstract
We studied the hormonal levels of newborns, during the third day of life in 47 SGA infants with a mean weight of 2.29 kgs. and mean length of 45.5 cms, and in 40 controls AGA infants with a mean weight of 3.37 kgs. and mean length of 49.1 cms.There were no significant differences between SGA and AGA newborns in the serum concentrations of Insulin: 45±5.4 vs 40±4.1 uUI/ml; Prolactin: 184±38 vs 162.8±51 ng/ml; T4: 13.1±3 vs 15.3±2.5 ug/dl; T3: 143±47 vs 151±42 ng/dl; Testosterone: 1.6±1.5 vs 1.2±1.1 ng/ml and Estradiol: 495±18.1 vs 501±23.4 pg/ml respectively, but there was a significant difference in IGF-I and IGF-II levels.It is known that IGF-I and to a lesser extent IGF-II in cord blood are correlated with newborn size. The higher plasma levels observed on the third day of life in SGA infants may signal the beginning of compensatory mechanisms of post natal growth in these children.
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