Abstract

A rapid, reliable method based on reversed-phase high performance liquid chromatography for the qualitative and quantitative determination of magnesium ascorbyl phosphate (VC-PMG) in both standard solutions and cosmetic products is reported. The procedure, based on an aminic stationary phase and acetonitrile-0.3 M phosphate buffer (pH 4) (40:60) as the mobile phase, allows the determination of VC-PMG in cosmetic samples after dilution with a tetrahydrofuran-0.3 M phosphate buffer (pH 4) (3:7) solvent mixture.

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