Abstract
(1) Background: Fracture causes a substantial burden to society globally. Some studies have found that soft drinks consumption was associated with the risk of fractures. We aimed to assess the association in the Chinese population; (2) Methods: Data from 17,383 adults aged 20 to 75 years old attending the China Health and Nutrition Survey (CHNS) between 2004 and 2011 were analyzed. Soft drinks consumption and fracture occurrence were self-reported. The cross-sectional and longitudinal associations between soft drink and fracture was assessed using multivariable mixed-effect logistic regression and Cox regression; (3) Results: After adjusting for sociodemographic and lifestyle factors and dietary patterns, compared with those who did not consume soft drinks, participants with daily consumption of soft drinks had an odds ratio (95%CI) of 2.72 (95%CI: 1.45–5.09) for fracture. During a mean 5-year follow-up, there were 569 incident fracture cases. Compared with non-consumers, those with daily soft drinks consumption had a hazard ratio (95%CI) of 4.69 (95%CI: 2.80–7.88) for incident fracture; (4) Conclusions: Soft drinks consumption is directly associated with the risk of fracture. Reducing soft drinks consumption should be considered as an important strategy for individual and population levels to maintain bone health.
Highlights
Musculoskeletal diseases such as fractures pose a serious global burden of disease
Soft drinks consumption was directly associated with fracture after adjusting for potential confounding factors
A high consumption of soft drinks is associated with fracture risk
Summary
Musculoskeletal diseases such as fractures pose a serious global burden of disease. Based on the Global Burden of Disease study, musculoskeletal illness accounted for 6.8% of total disability-adjusted life-years worldwide in 2010 [1]. In China, it has been estimated that more than 4 million people suffered from traumatic fractures in 2014 [2]. The average total medical cost due to fracture is estimated to be Renminbi (RMB) 18,853 per year per patient in China [3]. Within the 40 years, individuals at high risk of osteoporosis fractures (i.e., aged 50 years or older) will place a significant burden on society, in Asia [4]. The direct causes of fractures are accidental falls or hits, the fundamental causes are low bone density and excessive bone loss [5,6].
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