Abstract
Material and methods We investigated 40 students Stavropol State Medical University (16 boys and 24 girls) aged 19 to 22 who were divided into two groups: 1st group with no family history (12 people) and the 2nd group with heredity, burdened in the early CVD (28 people). The comparison group 21 people from the hospital cardiac patients with severe forms of ischemic heart disease. Family history was regarded as burdened by the presence of CVD in the immediate family, like hypertension, stroke, and various forms of ischemic heart disease in men aged up to 55 years for women and 65 years. Blood was tested to estimate the number of desquamated or circulating endothelial cells by the method of J. Hladovec (1978) and a study of the profile of modifiable cardiovascular risk factors was fulfilled. The results were processed statistically using the software package BIOSTAT. Results It turned out that the young people from the first group with a favorable inheritance of desquamated endothelial cells by an average of 2,6 ± 0,8, 2 median, mode 1, a maximum of 6 and a minimum of 1. These indicators are in the second group of students with a family history were equal respectively 5,8 ± 1,2, 4 median, mode 4, a maximum of 20 and a minimum of 2. That is, young people with a poor family history of the number of circulating endothelial cells was 2.2 times greater when compared with their peers who are not relatives of reported cases of early cardiovascular disease. These differences reached a statistically significant level (P ≥ 0,05). It is noteworthy that the number desquamated endothelial cells of patients with coronary artery disease is indicated by an average of 9,8 ± 1,5.
Highlights
IntroductionThe actuality In total mortality in all countries, almost 60% of deaths occur in cardiovascular disease (CVD) of atherosclerotic genesis [1]
Material and methods We investigated 40 students Stavropol State Medical University (16 boys and 24 girls) aged 19 to 22 who were divided into two groups: 1st group - with no family history (12 people) and the 2nd group - with heredity, burdened in the early cardiovascular disease (CVD) (28 people)
Young people with a poor family history of the number of circulating endothelial cells was 2.2 times greater when compared with their peers who are not relatives of reported cases of early cardiovascular disease
Summary
The actuality In total mortality in all countries, almost 60% of deaths occur in cardiovascular disease (CVD) of atherosclerotic genesis [1]. It is proved that the roots of these diseases a thing of the young and even children years of life [2,3], so it is advisable to start prevention in youth, which requires development of prenosological criteria for the diagnosis of age-appropriate
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