Abstract
1. The impact of 8–12 weeks exposure to up to 55–60 μg arsenic/g diet as disodium arsenate (DSA) on the hepatobiliary and hematological systems of rainbow trout was assessed. 2. Bile and washed gallbladder tissue arsenic residues in exposed fish were 2–4 times higher than in liver. Plasma arsenic concentration was slightly elevated following dietary DSA exposure. 3. Chronic exposure to dietary DSA caused a mild to moderate responsive anemia. 4. Lipid, but not protein, digestibility after 12 weeks of exposure showed an inverse relationship with severity of gallbladder inflammation in these fish. 5. Changes in the hepatobiliary system appear to provide the most sensitive indicators of dietary DSA exposure in rainbow trout.
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