Abstract

Screening constitutes the use of laboratory tests, physical examinations or imaging modalities performed on asymptomatic patients with the intent of identifying subclinical disease (1). As a result, screening differs from clinical investigation, in which tests are ordered after disease is suspected. A cancer screening program is a service in which everyone in a given population is (or has the opportunity to be) examined for the presence or precursor of a type of cancer. If the screening test finds that there is a likelihood of disease, a diagnostic test may be performed for confirmation (1).

Highlights

  • A cancer screening program is a service in which everyone in a given population is examined for the presence or precursor of a type of cancer

  • There are certain principles that are not fulfilled by chest computed tomography (CT) screening

  • There are three types of bias that are of interest when considering the use of helical CT in lung cancer screening – lead time bias, length time bias and overdiagnosis bias

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Summary

Introduction

A cancer screening program is a service in which everyone in a given population is (or has the opportunity to be) examined for the presence or precursor of a type of cancer. There are no studies demonstrating improved mortality in the group screened with helical chest CT. Treatment of early stage disease may not confer a mortality benefit. Significant morbidity and mortality may occur with resulting diagnostic procedures or treatments.

Results
Conclusion
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