Abstract
Heating analysis of soft tissue at finite deformation is of importance during treatment planning process for thermal ablation. This paper presents a method by combining non-Fourier bio-heat transfer and nonlinear biomaterial model to simulate thermal and mechanical responses of soft tissues under combined thermal and mechanical loads. At the same time, anisotropic feature of biological tissue is also concerned by including the stored energy of collagen fiber bundles into the traditional neo-Hookean free energy function. Simulation results demonstrate that in spite of relatively small thermal-induced displacement, the resultant thermal strain and stress contribution is nonnegligible and can be used as theoretical basis to measure tissue pain during thermal ablation process.
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