Abstract
Background: Patients with either osteoporosis or depression are prone to develop other diseases and require more medical resources than do the general population. However, there are no studies on health-related quality of life (HRQoL) and medical resource use by osteoporosis patients with comorbid depression. We conducted this study for clarifying it. Methods: This cross-sectional study from 2005 to 2010 (6 years) analyzed 9776 National Health and Nutrition Examination Survey (NHANES) patients > 40 years old. Each patient was assigned to one of four groups: osteoporosis-positive(+) and depression-positive(+) (O+/D+); O+/D−; O−/D+; O−/D−. We used multivariate linear and logistic regression model to analyze the HRQoL and medical resource use between groups. Results: The O+/D+ group reported more unhealthy days of physical health, more unhealthy days of mental health, and more inactive days during a specified 30 days. The adjusted odds ratios (AORs) of O+/D+ patients who had poor general health (7.40, 95% CI = 4.80–11.40), who needed healthcare (3.25, 95% CI = 2.12–5.00), and who had been hospitalized overnight (2.71, 95% CI = 1.89–3.90) were significantly highest. Conclusions: Low HRQoL was significantly more prevalent in D+/O+ patients. We found that depression severity more significantly affected HRQoL than did osteoporosis. However, both diseases significantly increased the risk of high medical resource use.
Highlights
Osteoporosis is a common skeletal disorder that leads to a systemic reduction of bone mass, strength, and skeletal microarchitecture [1], and it significantly increases the risk of fractures
More of them reported that their health was fair (40.14%) or poor (36.42%) and that they had more than four healthcare visits per year (79.58%), and more of them (39.44%) said that they had been hospitalized overnight often in the previous year
After we reviewed the data of a nationally representative sample of the United States (USA)’s population, we found that depression severity more significantly affected health-related quality of life (HRQoL) than did osteoporosis
Summary
Osteoporosis is a common skeletal disorder that leads to a systemic reduction of bone mass, strength, and skeletal microarchitecture [1], and it significantly increases the risk of fractures. The subsequent loss of mobility often causes a major reduction in health-related quality of life (HRQoL). Health Organization (WHO, Geneva, Switzerland) reported that osteoporosis is a major cause of serious health problems and increases mortality in elderly patients. Patients with either osteoporosis or depression are prone to develop other diseases and require more medical resources than do the general population. There are no studies on health-related quality of life (HRQoL) and medical resource use by osteoporosis patients with comorbid depression. Methods: This cross-sectional study from 2005 to 2010 (6 years) analyzed 9776 National Health and Nutrition Examination. Each patient was assigned to one of four groups: osteoporosis-positive(+) and depression-positive(+) (O+ /D+ ); O+ /D− ; O− /D+ ; O− /D−. We used multivariate linear and logistic regression model to analyze the HRQoL and medical resource use between groups.
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callMore From: International Journal of Environmental Research and Public Health
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
