Abstract
Previous study showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score. Therefore, this study aimed to determine the HRQoL of cervical cancer patients at Kenyatta National Hospital. A cross-sectional study design was employed among cervical cancer patients. All eligible consecutive samples of 103 cervical cancer patients were included in the study. Following consent, patients were interviewed using The European Organization for Research and Treatment of Cancer Quality-of-Life Questionnaire 30 (EORTC QLQ-30) and Cervical Cancer Module CX24 (EORTC QLQ-CX24). The data were entered and analyzed using the SPSS version 20.0 software. Univariate and multivariate binary logistic regression analysis was employed to investigate the predictors of HRQoL. A p-value of ≤ 0.05 was considered statistically significant. The majority (69%) of the patients had a poor overall quality of life while 31% of study participants had a good quality of life. Patients with early-stage disease were 7.3 times (AOR = 7.3, 95% CI = 2.4-21.7, p = 0.000) more likely to have a good HRQoL than patients with advanced-stage disease. Patients with no comorbidities were 3.1 times (COR = 3.1, 95% CI = 1.1-9.1, p = 0.037) more likely to have a good HRQoL than patients with comorbidities. The overall HRQoL among cervical cancer patients was poor in the setting. Advanced stage of disease and presence of comorbidities were the significant predictors of poor quality of life.
Highlights
A previous systematic review showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score
The overall health-related quality of life among cervical cancer patients was poor in the study setting
Advanced stage of disease and presence of comorbidities were the significant predictors of poor quality of life
Summary
A previous systematic review showed that health-related quality of life (HRQoL) was adversely affected during treatment of cervical cancer, with a worsening global score. This study aimed to determine the HRQoL of cervical cancer patients at Kenyatta National Hospital. The Catalan Institute of Oncology and the International Agency for Research in Cancer Information Centre on Human Papilloma Virus (HPV) and cancer approximate that every year 5250 females are diagnosed with cervical cancer, and 3286 dies from the condition [2]. Global Cancer Incidence, Mortality and Prevalence databases released in 2018 stated that ten years later, cervical cancer persists in being a major health issue, graded as the fourth most prevalent type of cancer and a significant cause of mortality among women [3]. According to a WHO report, 33 per 100,000 women aged between 15 and 44 in Kenya have cervical cancer, and 22 per 100,000 dies from the condition [1]
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