Abstract
IntroductionHashimoto's encephalopathy is a neurological disorder of unknown cause associated with thyroid autoimmunity. The disease occurs primarily in the fifth decade of life and may present in two types - a sudden vasculitic type or a progressive subacute type associated to cognitive dysfunction, confusion and memory loss.Case presentationWe report the case of a 62-year-old Hispanic woman, previously healthy, who developed a subacute onset of declining upper brain function. Serologic studies demonstrated high levels of antithyroid antibodies. Electroencephalographic and magnetic resonance image findings were consistent with Hashimoto's encephalopathy.ConclusionHashimoto's encephalopathy is a diagnosis of exclusion. This unusual disorder is often under-recognized because of the multiple and protracted neurocognitive manifestations; therefore, it is important to be aware of the clinical manifestations to make a correct diagnosis.
Highlights
ConclusionHashimoto’s encephalopathy is a diagnosis of exclusion. This unusual disorder is often underrecognized because of the multiple and protracted neurocognitive manifestations; it is important to be aware of the clinical manifestations to make a correct diagnosis
Hashimoto’s encephalopathy is a neurological disorder of unknown cause associated with thyroid autoimmunity
Hashimoto’s encephalopathy is a diagnosis of exclusion. This unusual disorder is often underrecognized because of the multiple and protracted neurocognitive manifestations; it is important to be aware of the clinical manifestations to make a correct diagnosis
Summary
HE frequently presents with a myriad of neurocognitive symptoms and normal findings in several different examinations. This syndrome may go unrecognized for a long time; it should be kept in mind when evaluating a patient with cognitive dysfunction and high titers of antithyroid antibodies
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