Abstract

Hand, foot and mouth disease (HFMD) is a viral illness caused most commonly in the past by coxsackievirus A16 and enterovirus 71. The disease mainly affects paediatric populations younger than 5 years of age and is characterized by lesions of the oral mucosa, palms and soles, lasting for 7–10 days. In recent years, coxsackievirus 6 has become a major cause of HFMD outbreaks in Ireland and worldwide. This strain causes more severe disease with unique findings compared with typical viral strains. We review the increasing presentation of patients with atypical cases in our institution and the implications.

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