Abstract
BACKGROUND: Propofol is the most common inducing agent for Laryngeal Mask Airway insertion but it causes haemodynamic instability.
 OBJECTIVE: To assess haemodynamic responses to insertion of Proseal Laryngeal Mask Airway (pLMA) with sodium thiopentone administration preceded by topical lignocaine and comparing with Propofol.
 METHODS: 100 patients of either sex in the age range of 16-60 years belonging to ASAI/II scheduled for open cholycystectomy were selected and allocated into one of the two groups. Group I (Propofol group) received Propofol 2.5mg/kg while as Group II (Thiopentone group) received topical lignocaine and intravenous sodium thiopentone for pLMA insertion. All patients received fentanyl 1μg/kg intravenously 3 minutes before induction. Haemodynamic parameters like pulse rate, mean systolic and diastolic blood pressures between the two groups were compared.
 RESULTS: The decrease in pulse rate, systolic and diastolic pressures in propofol group was more as compared to topical lignocaine and sodium thiopentone group while inserting pLMA. Number of attempts of pLMA insertion and oxygen saturation were same between the two groups when pLMA was inserted but the duration of apnoea was more in propofol than in topical lignocaine and sodium thiopentone group. Thus we concluded that sodium thiopentone administration preceded by topical lignocaine. (JMS 2010;13(2):56-59
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