Abstract
A study was conducted to evaluate the effect of condensed tannins and saponins from deoiled mahua seed cake (DMSC) on the development of fasciolosis. Fifteen male buffaloes were randomly divided into three groups of five each and were orally infected with Fasciola gigantica metacercaria at 800 per animal. DMSC was included in the concentrate mixture of group 2 (M5) and group 3 animals (M10) at 5 and 10%, respectively and group 1 remained as the non-supplemented control (C) group. Hypo-albuminemia, hyper-globulinemia and decrease in Albumin:Globulin (A:G) ratio were the significant features in C and M5 group. The group M10 was characterised by higher haemoglobin and packed cell volume and lower plasma total protein concentration, antibody response and faecal egg count than C and M5 group. This combined with higher plasma albumin, creatinine and lower globulin concentration in group 3 animals were conclusive of lower intensity infection as compared to other groups. It is concluded that condensed tannin and saponins of DMSC (10% of DMSC in concentrate mixture) possess remarkable anti-fasciolic activity.
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