Abstract
This guideline is an update of the post-exposure prophylaxis (PEP) guideline published by the Southern African HIV Clinicians Society in 2008. It updates the recommendations on the use of antiretroviral medications to prevent individuals who have been exposed to a potential HIV source, via either occupational or non-occupational exposure, from becoming infected with HIV. No distinction is made between occupational or non-occupational exposure, and the guideline promotes the provision of PEP with three antiretroviral drugs if the exposure confers a significant transmission risk. The present guideline aligns with the principles of the World Health Organization PEP guidelines (2014), promoting simplification and adherence support to individuals receiving PEP.
Highlights
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Preferred PEP regimen for children AZT + 3TC is recommended as preferred backbone for HIV PEP in children ≤ 35 kg
Lopinavir/ Ritonavir (LPV/r) is recommended as the third drug for HIV PEP in children
Summary
Read online: Scan this QR code with your smart phone or mobile device to read online. Affiliations: 1Wits Reproductive Health and HIV Institute, Johannesburg, South Africa HIV PEP regimens should contain three drugs
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