Abstract

To evaluate the utility of grey scale ultrasonography (US) and contrast enhanced ultrasonography (CEUS) forcharacterization of malignant gastric tumors. The study was conducted prospectively and it includeda number of 30 patients with malignant gastric tumors diagnosed through upper tract endoscopy and biopsy: 25 adenocarcinomas,3 lymphomas, and 2 stromal tumors. All the patients were examined by US, followed immediately by CEUS, usingboth oral and intravenous contrast agents. CEUS assessed the dynamics of the contrast agent during the arterial phase and thevenous phase. The distribution characteristics of the contrast agent inside the region of interest (ROI) were also evaluated.Twenty four patients underwent surgery. Adenocarcinomas presented heterogeneous enhancement with variable pattern,followed by a delayed wash-out in almost all of the situations. Lymphomas presented a variable pattern, intensity and homogeneityof the enhancement, followed by delayed wash-out. Stromal tumors showed early arterial intense and homogenousenhancement followed by moderate wash-out in venous phase. Grey scale US and CEUS are useful methods incharacterizing gastric tumors and contribute to a more adequate evaluation of the lesions. The dynamics of the contrast agentmay be suggestive for the anatomopathological nature of the tumor. Larger studies will be necessary in order to determine thepractical value of the method.

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