Abstract
Eco-friendly and inexpensive syntheses of metal-based nanocomposites is now gaining attention for their potential exploitation in biomedical and environmental fields. In this study, green method was applied to synthesize chitosan-modified platinum-doped silver nanocomposites (Ch-Pt-Ag NCs) using leaf extract of Desmostachya bipinnata, a plant with several medicinal values. Synthesis of Ch-Pt-Ag NCs was proven by XRD, SEM, FTIR, and TGA characterizations. Photocatalytic and biological activities of green-prepared Ch-Pt-Ag NCs were further explored. Crystallites of Ch-Pt-Ag NCs exhibited a mean size of 24 nm measured by XRD. SEM analysis indicated the formation of cubic and rod-shaped structures of Ch-Pt-Ag NCs. Functional groups present in plant extract were responsible for stabilizing and capping of Ch-Pt-Ag NCs, which were confirmed by FTIR analysis. Green synthesized Ch-Pt-Ag NCs exhibited dose-dependent anti-inflammatory and larvicidal (anti-dengue) activities. Green prepared Ch-Pt-Ag NCs exerted very low toxicity in Brine shrimp lethality assay indicated the biocompatible nature of synthesized nanostructures. The Ch-Pt-Ag NCs were also examined as a photocatalytic agent, resulting in 98% degradation of Rhodamine dye. Green synthesized Ch-Pt-Ag NCs with great biological and photocatalytic activities warrants further research on its biomedical and environmental fields.
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