Abstract
The study reports the synthesis of silver nanoparticles (AgNPs) using green method where plant extracts of Turmeric, curry-leaves, Ashwagandha, Arjun, Aloe vera and Tulsi were used as reducing agents. Characterization was done using UV-Visible spectroscopy and Scanning electron microscopy. UV-Visible spectrum showed peak absorbance around 420nm and SEM-EDAX analysis confirmed the presence of AgNPs in a size range of 50-80nm. Ability of the synthesized AgNPs as an antimicrobial agent was studied and their use was extended to the treatment of contaminated water. It was found that 30μL of AgNPs effectively decontaminated water containing 103 CFU/mL E. coli within 10 minutes. The study also focuses on the effect of the nanoparticles on the growth of Saccharomyces cerevisiae as a model organism for eukaryotic cells. No significant effect on the growth of S. cerevisiae was observed. Effect of AgNPs on advanced glycation end-products (AGEs) was also studied. AGEs are formed due to non-enzymatic glycation in hyperglycemic conditions leading to secondary complications in diabetes. AgNPs synthesized using Ashwagandha, curry-leaves and Aloe vera showed anti-glycating properties in a concentration dependent manner. This suggests that these properties of AgNPs may be used in many environmental and therapeutic applications but their use should be regulated and studied in detail.
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