Abstract
Cancer is the deadliest health problem after cardiovascular system diseases. New strategies have been developed over the years in the fight against cancer. Silver nanoparticles are one of these approaches. In this study, it was aimed to synthesize silver nanoparticles with the green approach using Elaeagnus angostifolia aqueous extract and to investigate the cytotoxic effects of these nanoparticles. Silver nanoparticles have been characterized by analytical methods such as UV-Vis, FTIR, SEM, EDX. The peak around 3 keV in the EDX spectrum confirms the synthesis of silver nanoparticles. In vitro cytotoxic activity of silver nanoparticles was tested on human prostate cancer cell line PC3, human cervical cancer cell line HELA and normal mouse fibroblast cell line L929. It has been found that silver nanoparticles synthesized with the aqueous extract of Elaeagnus angustifolia showed a dose-dependent cytotoxic effect on HELA and PC3 cells.
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