Abstract

Objective To investigate the clinicopathologic features, diagnosis and differential diagnosis of granulocytic sarcoma (GS) of the vulva. Methods One patient with GS of the vulva was analyzed on morphological characteristics, immunohistochemical stainings and clinical data with review of the literature. Results The patient was a 75-year-old lady. She was admitted to the hospital for a painless lump found in her left vulvar region. B-ultrasound revealed a solitary isoechoic mass at she left labia minora with an internal heterogeneous echo. Grossly, the tumor was described as a solid neoplasm with fish-fresh like cut surface and an ill-defined margin. Microscopically, the malignant cells grew in a diffuse sheet pattern and were small to medium in size, with scant cytoplasm. The nuclei were round or oval, and had finely dispersed chromatin. The mitotic rates were high. Immunohistochemically, the tumour cells expressed for myeloperoxidase (MPO), CD43, lysozyme and CD117. Conclusions GS of the vulva is extremely rare. In routine histopathology, it may be misdiagnosed as lymphoma, Ewing sarcoma and small cell carcinoma et al. Awareness of the morphology and precise diagnosis of GS of the vulva have significance for appropriate treatment and prognosis of the patients. Key words: Vulvar neoplasms; Sarcoma, maeloid; Pathology, clinical; Diagnosis, differential

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.