Abstract
We describe the case of a 55 year old female who presented with a mass in her right breast. Mammography confirmed a 2 × 2 cm lump, suspicious of malignancy. The lesion was widely resected. Histological examination revealed this to be a benign granular cell tumour.Granular cell tumour is a rare tumour that very occasionally presents within the breast. It is possibly of Schwann cell origin. Clinical features and subsequent investigations may be suggestive of breast malignancy. Tumour cells showing positive immunostaining for S-100 and PAS is in keeping with the diagnosis. Wide local resection is the gold standard treatment.
Highlights
Granular cell tumour (GCT) was first described in 1926 by Abrikosoff as a rare myogenic lesion affecting the tongue
We present a case of GCT of the pectoral muscle mimicking breast cancer in a female patient, highlighting the diagnostic challenge and the treatment options in managing patients with GCT
There are a limited number of reported cases in the English literature the frequency of GCT is estimated to be 1 per 1000 cases of breast cancer [2]
Summary
Granular cell tumour (GCT) was first described in 1926 by Abrikosoff as a rare myogenic lesion affecting the tongue. A 55 year old female presented with a 2 month history of a painless lump in her upper outer quadrant of her right breast. She was on hormone replacement therapy for the previous 4 years. Mammography and ultrasound imaging showed a suspicious lesion in the upper outer quadrant of the right breast which appeared to be attached to the underlying pectoralis major muscle [Figure 1 and 2]. Mammogram shows a dense mass deep in the upper outer quadrant of the right breast adjacent to the pectoralis major muscle.
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