Abstract
In this paper, glutathione capped Mn2+-doped ZnSe quantum dots (QDs) were conjugated with nitric oxide (NO) photosensitive-donors (Fe4S3(NO)7−, RBS) to fabricate QDs-RBS nanocomposites under electrostatic interactions. The QDs-RBS presented marked two-photon excited fluorescence (TPEF, peaked at 570 nm) upon two-photon excitation (with 1130 nm laser). The TPEF emitting from QDs in QDs-RBS could trigger the RBS photolysis to release NO. By regulating excitation power and irradiation time, the QDs-RBS showed controllable NO release in water-soluble environments. Upon two-photon excitation, the QDs-RBS also demonstrated high growth inhibition to cancer cells. Experimental results revealed that the TPEF (570 nm) of QDs efficiently triggered the release of NO from RBS, and the released NO induced significant cytotoxicity to cancer cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
