Abstract
Objectives: Endometrial cancer (EC) has been recognized as a major cancer component in Cowden syndrome (CS), which is classically associated with germline PTEN mutations. Germline SDHB/C/D (SDHx) variation and KLLN promoter methylation have been recently reported in CS and CS-like (CSL) patients. The aim of this study was to identify the prevalence and clinico-athologic features predictive of germline SDHx and KLLN alterations in CS and CSL patients with EC.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
