Abstract
Comorbidity indices and performance status (PS) have been the primary tools used to predict HCT tolerance; however, these tools suffer from poor discriminative capacity. Geriatric Assessment (GA) has found widespread application to assess reduced physiologic reserve (i.e. vulnerability) among elderly adults. We hypothesized that a modified GA would identify vulnerable HCT recipients 50 years and older. We supplemented the standard pre-HCT evaluation (e.g. history, laboratory, PFT's) with a prospective GA integrating multiple geriatric domains.
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