Abstract

A survey of buccal cavity and pharynx cancer mortality in United States counties. 1950–1969, revealed elevated rates among males in urban areas throughout the country and among females in the rural South. Indirect evidence suggests that the urban gradient in males results largely from alcoholic beverage consumption and tobacco smoking, while the Southern excess in females is related primarily to oral snuff use. Mortality was elevated also in counties with leather, paper, and chemical manufacturing industries (in males), and apparel and textile industries (in females). The industrial correlations in both sexes remained after control for urbanization and other demographic factors, but snuff use by Southern women in the textile and apparel industries may have influenced this association for females.

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