Abstract

Alcohol use disorder (AUD) is a widespread disease, but molecular pathogenesis of AUD remains incompletely understood, and there are no efficient medications to treat AUD. Long non-coding RNAs (lncRNAs) are RNA molecules >200 nucleotides with no coding potential. LncRNAs control key transcriptional and posttranscriptional processes, thus regulating the formation of transcriptome. We tested the hypothesis that AUD affects transcriptome via changes in lncRNAome.

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