Objective To investigate the genetic polymorphisms of 15 short tandem repeat(STRs) in Guilin Han population. Methods DNA was extracted by Chelex method, and 15 STRs were analyzed using AmpFISTR IdentifilerTM kit. Results Four rare alleles, namely FGA*10, D2S1338*10, D3S1358*16.2 and D3S1358 * 17.2, were observed. The combined match probability and exclusion probability for the 15 STRs were 2.89×10-17 and 0. 9999993, respectively. Conclusion These STRs have good discrimination power and exclusion probability in Guilin Hart population. Key words: short tandem repeat;  genetic polymorphism;  genotyping

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