Abstract
Nath, M., Singh, B.P., Saxena, V.K., Singh, R.V. and Dev Roy, A.K. 2001. Genetic analysis of concanavalin-A response in broilers. J. Appl. Anim. Res. 20: 171–180. To evaluate the crossbreeding parameters in respect to in vivo mitogen response in broiler, a complete 4x4 diallel design was followed using four synthetic broiler lines namely Coloured Synthetic Male Line (CSML), White Synthetic Male Line (WSML), Coloured Synthetic Female Line (CSFL) and Naked Neck Line (NNL). The in vivo cell-mediated immune response to the mitogen concanavalin-A (Con-A) was evaluated injecting 0.1ml of Con-A (lmg Con-A in 1ml of phosphate buffer saline) inter-digitally and the foot index was calculated. The results indicated that both additive and non-additive genetic variation attributed to minor genes at many loci is important, for the genetic control of in vivo Con-A response in chicken. Total non-additive components of variance also showed significant amount of heterosis in crossbred progenies. Therefore, it may be concluded that the exploitation of non-additive component of variance is possible for improvement in cell-mediated immunity in broilers.
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