Abstract
A 24-year-old man presented with itchy verrucous, scaly red-brown papules, & linear plaques distributed in a blaschkoid pattern all over the body since last 20 years associated with itching. A skin biopsy was consistent with ILVEN (inflammatory linear verrucous epidermal nevus). Histopathologically, it can be difficult to distinguish it from linear psoriasis. It may respond to conventional anti-psoriatic therapies like potent topical corticosteroids applied under occlusion, or systemic treatments like acitretin.
Highlights
Inflammatory linear verrucous epidermal nevus (ILVEN) is a pruritic, erythematous scaly lesion following Blaschko’s lines & characterized by an eczematous or psoriasiform papules variable length, occasionally extending the whole length of a limb
The pathogenesis of ILVEN is not clear, but it could be explained by the well-established concept of genetic mosaicism
There was no history of psoriasis or any other skin disease in the family
Summary
Inflammatory linear verrucous epidermal nevus (ILVEN) is a pruritic, erythematous scaly lesion following Blaschko’s lines & characterized by an eczematous or psoriasiform papules variable length, occasionally extending the whole length of a limb. A 24 years old male presented with 20 years history of pruritic, non-discharging, erythematous, papulosquamous and verrucous lesions all over the body (Figure-1), (Figure-2). There was no history of injury or any other previous eruption at the site of present lesions. Upper dermal perivascular lymphocytic infiltrate with few neutrophils is present. He responded partially to Isotretinoin 40 mg daily along with topical steroids & keratolytics. Generalized ILVEN or blaschkoid psoriasis: A persistent dilemma.
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