Abstract
8100 Background: Baseline differences in red blood cell mass between men and women may need to be considered in the management of cancer-related anemia with recombinant human erythropoetin (rHuEPO) for QoL benefit. Methods: Valid information on patient fatigue was collected from 197 patients with solid tumors via the Functional Assessment of Cancer Therapy - Anemia (FACT - An) subscale questionnaire. Additional patient information including diagnosis, age, gender, Eastern Cooperative Oncology Group (ECOG) performance status, current therapy, and hemoglobin level was recorded and considered for a possible role in patient fatigue. Results: Hemoglobin concentration was positively correlated with FACT-An subscale score (p < .001), as were improvements in ECOG performance status by regression analysis (p < .001). Patients receiving chemotherapy experienced greater fatigue than those who were not by independent t-test (p < .01). Regression analysis revealed that patient age did not have a statistically signific...
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