Abstract
Proteinas G: potencial papel terapeutico A liberacao de oxido nitrico (NO) pode ocorrer por diferentes vias envolvendo proteinas G. A proteina Gi e responsavel pela mediacao dos efeitos inibitorios dos receptores nas vias adenilato ciclase e guanilato ciclase. Um estagio inicial da maioria das respostas mediadas por receptores e a ativacao das proteinas G na membrana celular, alvo da modulacao de uma variedade de eventos intracelulares. O papel das proteinas G na fisiopatologia do vasoespasmo apos isquemia global e reperfusao [...]
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