Abstract

Pancreas arises from dorsal and ventral anlagen, and there is an embryological fusion plane between them. The embryological fusion plane can be discriminated by immunohistochemical staining for an anti-pancreatic polypeptide or computed tomography. The embryological fusion plane can not only guide the management of benign or low malignant potential tumors, but also determine the clinicopathological characteristics of pancreatic head cancer and patients' survival, and the embryological fusion plane plays an important role in the management of pancreatic disease. In this review, the research progressions and clinical significance in the embryological fusion plane of dorsal and ventral pancreas are described. Key words: Pancreatic neoplasms; Dorsal pancreas; Ventral pancreas; Fusion plane

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