Abstract
The kinetics of incorporation of 14C-valine in the sea urchin embryo have been studied particularly with respect to the time course of incorporation and the effect of exogenous valine on incorporation of 14C-valine from the amino acid pool. The data are interpreted as reflecting a rapid and continual expansion of the valine pool in the presence of exogenous valine. All kinetic aspects, the apparent linearity of the time course of incorporation, the nonlinear relationship of uptake and incorporation at different concentrations of exogenous valine, and the apparent cessation of incorporation of pool valine in the presence of exogenous valine, can be satisfactorily interpreted by the concept of a readily expansible valine pool. An earlier interpretation that the intracellular amino acid pool is compartmented as regards protein synthesis is untenable, and it is concluded that the total amino acid pool is an obligatory intermediate for incorporation of exogenous amino acids.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
