Abstract
Some unusual patterns of chiasma distribution were noted in a preliminary investigation of meiosis in an infertile male with an apparently normal mitotic karyotype and a normal mean autosomal cell chiasma frequency. A detailed investigation of chiasma distribution on all 22 autosomes revealed that several chromosomes showed a significant change in chiasma distribution and/or mean inter-chiasma distance in comparison with previously published controls. These findings are discussed in relation to the general patterns of chiasma localization in the human male and the role of interference.
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