Abstract

My purpose in this paper is to present further proof that the mucous membrane in the human antrum regenerates following radical operation and to throw some light on the method whereby this regeneration is accomplished. I have always believed that the new lining of the antrum after a radical operation is for the most part scar tissue. The experiments that Dr. Knowlton and I carried out on dogs were performed to find out what actually happens. They demonstrated that the mucous membrane of the antrum regenerates and is histologically normal. The regenerated mucous membrane must, of course, come from islands left at operation or grow in from the nose. Some investigators who have discussed the question of regeneration have spent much time on these two points. The whole point of this paper and of the one that preceded it is that after removal mucous membrane regenerates and is

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