Abstract

It is a striking fact that lactose is found in but one place in nature, in the mammary secretion, milk. More information may well be obtained about it and its products of hydrolysis, particularly the galactose moiety. Several investigators have found that tolerance for galactose is less than for a mixture of glucose and galactose. The evidence presented has been the decreased urinary excretion and the less striking change in the blood sugar when glucose accompanied the galactose. One objection to such observations, and a limitation to their interpretation, lies in the absence of knowledge of what changes in galactose concentration of the blood and urine are taking place.A method for the estimation of galactose in blood and urine has been developed,1 and applied in an effort to learn more of the relationship between the metabolism of glucose and galactose. Glucose injected simultaneously with galactose has increased the rate of removal of the latter from the blood, but the effect could be explained at leas...

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